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Water → 3-(2',4'-Difluoro-4-biphenylyl)butyric acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 1-Hexanol | HCID 8103 | — |
| 反応物 | 3-(2',4'-Difluoro-4-biphenylyl)butyronitrile | HCID 21322521 | — |
| 生成物 | 3-(2',4'-Difluoro-4-biphenylyl)butyric acid | HCID 21322540 | — |
反応手順
1 g. of 3-(2',4'-difluoro-4-biphenylyl)butyronitrile, 3 ml. of n-hexanol and 0.1 g. of concentrated H2SO4 are heated under reflux for 48 hours. 3 ml. of water are added and the mixture is heated under reflux for 48 hours more and worked up in the customary manner to give 3-(2',4'-difluoro-4-biphenylyl)-butyric acid, m.p. 109°-110°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04151302 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-ac0eb0931272464d9cce0fa5ac820a65 |
| 出典メモ | uspto-grants-1979_04 |