関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Pentyltriphenylphosphonium bromide | HCID 2724565 | — |
| 反応物 | Potassium bis(trimethylsilyl)amide | HCID 3251421 | — |
| 反応物 | 1-(3,5-Dimethoxyphenyl)-1-(hex-1-enyl)-cyclopentane | HCID 69204664 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | (Butylmethylene)triphenylphosphorane | HCID 10980496 | — |
反応手順
To a suspension of pentyltriphenylphosphonium bromide (5 equiv.) in dry THF (0.1 8M) at 0° C., under an argon atmosphere was added potassium bis(trimethylsilyl) amide (4.9 equiv.). The mixture was warmed to 10° C. and stirred for an additional 30 min to ensure complete formation of the orange ylide. The resulting slurry was used in the preparation of 1-(3,5-dimethoxyphenyl)-1-(hex-1-enyl)-cyclopentane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07446229B2 |
|---|
| 出典データセット | uspto-grants-2008_11 |
|---|
| ORD ID | ord-8a265133726f4b34870e605b378255b7 |
|---|
| 出典メモ | uspto-grants-2008_11 |
|---|
