Ethanol → 2-Bromo-5-chlorobenzoic acid ethyl ester

HRID 269554

反応式

HRID 269554 の反応式
[Br:1][C:2]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH2:12](O)[CH3:13]>S(=O)(=O)(O)O>[Br:1][C:2]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:3]=1[C:4]([O:6][CH2:12][CH3:13])=[O:5]

参加物

4

反応物 2

HCID 702EthanolHCID 890272-Bromo-5-chlorobenzoic acid

生成物 1

HCID 693095662-Bromo-5-chlorobenzoic acid ethyl ester

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

A solution of 2-bromo-5-chlorobenzoic acid in ethanol (10 ml) and sulphuric acid (0.5 ml) was refluxed for 20 hours then cooled and evaporated. The residue was dissolved in diethyl ether/water and the organic layer dried (magnesium sulphate) and evaporated to give 516 mg of light brown oil.

後処理

  1. temperaturethen cooled
  2. customevaporated
  3. dissolutionThe residue was dissolved in diethyl ether/water
  4. dry with materialthe organic layer dried (magnesium sulphate)
  5. customevaporated

出典と根拠

ORDレコード
ord-53864e97ac024a7b8db7f1a8a5c79c24
出典データセット
uspto-grants-2008_11
特許番号
US07446222B2

関連ノート

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