化工社化工社 化学情報印刷レポート · 研究参考用
Trifluoroacetic acid → Morpholin-2-ylmethyl trifluoroacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | tert-Butyl 2-(hydroxymethyl)morpholine-4-carboxylate | HCID 5201202 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Morpholin-2-ylmethyl trifluoroacetate | HCID 11206644 | — |
反応手順
Tert-Butyl 2-(hydroxymethyl)-4-morpholinecarboxylate (5.13 g, 23.61 mmol) was treated with CF3CO2H (20 mL) in CH2Cl2 (50 mL) at room temperature for 3 h. The volatiles were removed in vacuo to give the subtitled compound (7.6 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07449475B2 |
| 出典データセット | uspto-grants-2008_11 |
| ORD ID | ord-cd13a1f2c918407faf5b11bd981b00ae |
| 出典メモ | uspto-grants-2008_11 |