Triethylamine → HCID 86601487、化合物
反応式
[OH:1][N:2]1[C:6](=[O:7])[C:5]2=[CH:8][CH:9]=[CH:10][CH:11]=[C:4]2[C:3]1=[O:12].[N+](C1C=C(S(O[CH2:26][C@:27]2([CH3:30])[CH2:29][O:28]2)(=O)=O)C=CC=1)([O-])=O.C(N(CC)CC)C>ClCCl>[CH3:26][C@@:27]1([CH2:30][O:1][N:2]2[C:3](=[O:12])[C:4]3[C:5](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6]2=[O:7])[CH2:29][O:28]1参加物
5
実験手順
A mixture of N-hydroxypthalimide (5.3 g, 32.5 mmol), [(2S)-2-methyloxiran-2-yl]methyl 3-nitrobenzenesulfonate (5.9 g, 21.6 mmol) and triethylamine (10.6 ml) in dichloromethane (15 ml) was stirred under nitrogen at ambient temperature for 24 h. The reaction mixture was poured onto a silica column and eluted with dichloromethane to give the sub-title compound as a colourless solid (3.1 g).
後処理
- additionThe reaction mixture was poured onto a silica column
- washeluted with dichloromethane
出典と根拠
- ORDレコード
- ord-c6e78bb1857e4652883bb92d5f0b3d3d
- 出典データセット
- uspto-grants-2008_11
- 特許番号
- US07449475B2
反応ノート
読み込み中…