(Cyclopropylmethyl)methylamine → {4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-cyclopropylmethyl-methyl-amine

HRID 270309

反応式

HRID 270309 の反応式
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:22]=[CH:21][C:10]2[C:11]([C:14]3[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=3)=[N:12][S:13][C:9]=2[CH:8]=1.[CH3:23][NH:24][CH2:25][CH:26]1[CH2:28][CH2:27]1>>[Cl:20][C:17]1[CH:18]=[CH:19][C:14]([C:11]2[C:10]3[CH:21]=[CH:22][C:7]([O:6][CH2:5][CH2:4][CH2:3][CH2:2][N:24]([CH2:25][CH:26]4[CH2:28][CH2:27]4)[CH3:23])=[CH:8][C:9]=3[S:13][N:12]=2)=[CH:15][CH:16]=1

参加物

3

反応物 2

HCID 12919209(Cyclopropylmethyl)methylamineHCID 223139036-(4-Bromo-butoxy)-3-(4-chloro-phenyl)-benzo[d]isothiazole

生成物 1

HCID 69287998{4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-cyclopropylmethyl-methyl-amine

実験手順

According to the method in example 7, 6-(4-Bromo-butoxy)-3-(4-chloro-phenyl)-benzo[d]isothiazole and N-Methylcyclopropanemethylamine were converted to yield {4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-cyclopropylmethyl-methyl-amine, MS: 401 (MH+, 1Cl).

出典と根拠

ORDレコード
ord-5a87ac047a874f56b0ed8a0b4c4ac96e
出典データセット
uspto-grants-2008_11
特許番号
US07449483B2

関連ノート

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