1,4-Dibromobutane → 6-(4-Bromo-butoxy)-2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophene
反応式
[CH3:1][C:2]1[S:6][C:5]2[CH:7]=[C:8]([OH:11])[CH:9]=[CH:10][C:4]=2[C:3]=1[C:12]1[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][CH:13]=1.[Br:22][CH2:23][CH2:24][CH2:25][CH2:26]Br>>[Br:22][CH2:23][CH2:24][CH2:25][CH2:26][O:11][C:8]1[CH:9]=[CH:10][C:4]2[C:3]([C:12]3[CH:13]=[CH:14][C:15]([C:18]([F:21])([F:19])[F:20])=[CH:16][CH:17]=3)=[C:2]([CH3:1])[S:6][C:5]=2[CH:7]=1参加物
3
実験手順
In analogy to example 27.1, 2-Methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-ol and 1,4-dibromobutane were converted to yield 6-(4-Bromo-butoxy)-2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophene as colorless oil, MS: 443 (MH+, 1Br).
出典と根拠
- ORDレコード
- ord-9b92145bab354f2ab9b65039cf3ff3e0
- 出典データセット
- uspto-grants-2008_11
- 特許番号
- US07449483B2
反応ノート
読み込み中…