3-Butyn-1-OL → HCID 22314043、化合物

反応式

[CH3:1][C:2]1[S:6][C:5]2[CH:7]=[C:8](OS(C(F)(F)F)(=O)=O)[CH:9]=[CH:10][C:4]=2[C:3]=1[C:19]1[CH:24]=[CH:23][C:22]([C:25]([F:28])([F:27])[F:26])=[CH:21][CH:20]=1.[CH2:29]([OH:33])[CH2:30][C:31]#[CH:32]>>[CH3:1][C:2]1[S:6][C:5]2[CH:7]=[C:8]([C:32]#[C:31][CH2:30][CH2:29][OH:33])[CH:9]=[CH:10][C:4]=2[C:3]=1[C:19]1[CH:20]=[CH:21][C:22]([C:25]([F:27])([F:28])[F:26])=[CH:23][CH:24]=1

参加物

反応物 2

HCID 135663-Butyn-1-OL

HCID 86585425HCID 86585425、化合物

生成物 1

HCID 22314043HCID 22314043、化合物

実験手順

In analogy to example 13.1, the Trifluoro-methanesulfonic acid 2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yl ester was reacted with 3-butyn-1-ol to yield the 4-[2-Methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yl]-but-3-yn-1-ol as brown oil, MS: 360 (M+).

出典と根拠

ORDレコード: ord-abca2916df3a47369c6dcfcd82352942
出典データセット: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07449483B2

反応ノート

読み込み中…