Oxazole, 5-(2-chloroethyl)-4-methyl- → HCID 70543535、化合物

HRID 27100ノート

反応式

HRID 27100 の反応式
ClCCC1OC=[N:6]C=1C.[N+:10]([CH:13]=[C:14]([NH:27][CH3:28])[NH:15][CH2:16][CH2:17][S:18][CH2:19][CH2:20][C:21]1[O:25][CH:24]=[N:23][C:22]=1C)([O-:12])=[O:11].NC1OC(CCCl)=CN=1>>[N+:10]([CH:13]=[C:14]([NH:27][CH3:28])[NH:15][CH2:16][CH2:17][S:18][CH2:19][CH2:20][C:21]1[O:25][C:24]([NH2:6])=[N:23][CH:22]=1)([O-:12])=[O:11]

参加物

4

反応物 3

HCID 120387Oxazole, 5-(2-chloroethyl)-4-methyl-HCID 205501432-Amino-5-(2-chloroethyl)oxazoleHCID 70544414HCID 70544414、化合物

生成物 1

HCID 70543535HCID 70543535、化合物

実験手順

Using 5-(2-chloroethyl)-4-methyloxazole as starting material in the procedure of Example 21 the product is 1-nitro-2-methylamino-2-[2-(2-(4-methyl-5-oxazolyl)ethyl)thioethylamino]ethylene. Also, using 2-amino-5-(2-chloroethyl)oxazole (prepared by reacting 2-amino-5-(2-hydroxyethyl)oxazole with thionyl chloride) in the procedure of Example 21 gives 1-nitro-2-methylamino-2-[2-(2-(2-amino-5-oxazolyl)ethyl)thioethylamino]ethylene

出典と根拠

ORDレコード
ord-4951e5f41e564b50aaa1b2e319dc90c5
出典データセット
uspto-grants-1980_09
特許番号
US04220652

反応ノート

読み込み中…