6-Chloromethyl-2-methylpyridinium chloride → 2-[4-(3-Chloro-phenylethynyl)-2-methyl-imidazol-1-ylmethyl]-6-methyl-pyridine

反応式

[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:6][CH:7]=1.Cl.Cl[CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH3:25])[N:20]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([CH3:25])[N:20]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

参加物

反応物 2

HCID 765456-Chloromethyl-2-methylpyridinium chloride

HCID 178432693HCID 178432693、化合物

生成物 1

HCID 113362252-[4-(3-Chloro-phenylethynyl)-2-methyl-imidazol-1-ylmethyl]-6-methyl-pyridine

実験手順

The title compound, MS: m/e=322.4 (M+H30), was prepared in accordance with the general method of example 1 from 4-(3-chloro-phenylethynyl)-2-methyl-1H-imidazole and 2-chloromethyl-6-methyl-pyridine hydrochloride.

出典と根拠

ORDレコード: ord-63b078c3ce3e45bba82134b7760faf62
出典データセット: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07452909B2

反応ノート

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