Potassium Carbonate → 6-[(R)-3-(4-chloro-benzyl)-4-isopropyl-2,5-dioxo-imidazolidin-1-ylmethyl]-7-(2,2-dimethyl-propyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile

反応式

Br[CH2:2][C:3]1[N:13]([CH2:14][C:15]([CH3:18])([CH3:17])[CH3:16])[C:6]2[N:7]=[C:8]([C:11]#[N:12])[N:9]=[CH:10][C:5]=2[CH:4]=1.[Cl:19][C:20]1[CH:36]=[CH:35][C:23]([CH2:24][N:25]2[C@H:29]([CH:30]([CH3:32])[CH3:31])[C:28](=[O:33])[NH:27][C:26]2=[O:34])=[CH:22][CH:21]=1.C([O-])([O-])=O.[K+].[K+]>CN(C=O)C.C(OCC)(=O)C>[Cl:19][C:20]1[CH:21]=[CH:22][C:23]([CH2:24][N:25]2[C@H:29]([CH:30]([CH3:32])[CH3:31])[C:28](=[O:33])[N:27]([CH2:2][C:3]3[N:13]([CH2:14][C:15]([CH3:18])([CH3:17])[CH3:16])[C:6]4[N:7]=[C:8]([C:11]#[N:12])[N:9]=[CH:10][C:5]=4[CH:4]=3)[C:26]2=[O:34])=[CH:35][CH:36]=1