1-(2,6-Dichlorophenyl)3-(t-butylcarbamyl)thiourea → 1-(2,6-Dichlorophenyl)-3-carbamylthiourea
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:19])[NH:14]C(C)(C)C)=[S:11]>Cl>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:19])[NH2:14])=[S:11]参加物
3
実験手順
A mixture of 32 g (0.1 mole) of 1-(2,6-dichlorophenyl)3-(t-butylcarbamyl)thiourea and 200 ml of conc. hydrochloric acid is refluxed for 1/2 hour. The reaction mixture is cooled, filtered and washed with 10 ml of 1:1 HCl/H2O and dried. The product is then recrystallized from ethanolether to obtain 1-(2,6-dichlorophenyl)-3-carbamylthiourea.
後処理
- temperatureis refluxed for 1/2 hour
- temperatureThe reaction mixture is cooled
- filtrationfiltered
- washwashed with 10 ml of 1:1 HCl/H2O
- customdried
- customThe product is then recrystallized from ethanolether
出典と根拠
- ORDレコード
- ord-d9aba9dc1f5342419a7a05c7b9e05b13
- 出典データセット
- uspto-grants-1980_09
- 特許番号
- US04220658
反応ノート
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