関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Urea | HCID 1176 | — |
| 反応物 | 2-[4-(Dimethylamino)phenyl]-2-hydroxy-1-phenylethanone | HCID 590628 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 4-(4-dimethylaminophenyl)-2,3dihydro-5-phenyl-1H-imidazol-2-one | HCID 54011565 | — |
反応手順
To acetic acid (2 mL) was added urea (0.6 g, 10 mmol) and 2-(4-dimethylaminophenyl)-2-hydroxy-1-phenylethanone (2.6 g, 10 mmol). After stirring for 2 hours at 120° C., the reaction was cooled to ambient temperature. The resulting solid was filtered, washed with ether, and dried in vacuo to give 4-(4-dimethylaminophenyl)-2,3dihydro-5-phenyl-1H-imidazol-2-one; NMR (CDCl3) 10.98 (s,2), 7.5 (m,4), 7.4 (m,5), 3.18 (s,6) ppm.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05731311 |
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| 出典データセット | uspto-grants-1998_03 |
|---|
| ORD ID | ord-4eef7a1f326e44c69373eeaaece2675b |
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| 出典メモ | uspto-grants-1998_03 |
|---|
