関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Aripiprazole | HCID 60795 | — |
| 溶媒 | 1,2-Dichloroethane | HCID 11 | — |
| 生成物 | Aripiprazole ethylenedichloride | HCID 11489682 | 136.5% |
反応手順
Aripiprazole (3 gm) is mixed with ethylenedichloride (30 ml) and heated to 50° C. to form a clear solution. The solution is slowly cooled to 25° C., stirred for 1 hour at about 25° C. and the separated crystals are collected by filtration to give 2.5 gm of aripiprazole ethylenedichloride solvate form V.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07456181B2 |
|---|
| 出典データセット | uspto-grants-2008_11 |
|---|
| ORD ID | ord-96181f3c68c34f33896c55e67d1d75aa |
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| 出典メモ | uspto-grants-2008_11 |
|---|
