化工社化工社 化学情報印刷レポート · 研究参考用
Diisopropylethylamine → Benzodiazepinesuccinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diisopropylethylamine | HCID 81531 | — |
| 反応物 | Benzodiazepine | HCID 134664 | — |
| 反応物 | HCID 131723749 | HCID 131723749 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Benzodiazepinesuccinamide | HCID 136334626 | — |
反応手順
Following the procedures described for the synthesis of 11, diallylsuccinamide intermediate 16 was prepared from 14 in reasonable yield. 14 (2.59, 5.9 mmol), p-chloro-BZD (2.34 g, 6.2 mmol) and DIPEA (1 ml, 5.8 mmol) in 30 ml DMF was heated to 40-50 degree overnight.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07456278B2 |
| 出典データセット | uspto-grants-2008_11 |
| ORD ID | ord-2f787a2ae6ec41138582c97c2046094a |
| 出典メモ | uspto-grants-2008_11 |