1-Methyl-7-benzoylindoline → 1-Methyl-7-benzoylindole
反応式
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[C:11](=[O:18])[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:4][CH2:3]1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[C:11](=[O:18])[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:4]=[CH:3]1参加物
4
実験手順
A mixture of 2.4 grams (0.01 mole) of 1-methyl-7-benzoylindoline and 8.7 grams (0.1 mol) of manganese dioxide in 25 ml of methylene chloride was heated at reflux for 18 hours. The mixture was cooled and filtered. The filtrate was concentrated and the resulting residue was distilled to give 2 grams of 1-methyl-7-benzoylindole having a b.p. of 128° C./0.03 mm Hg.
後処理
- temperaturewas heated
- temperatureat reflux for 18 hours
- temperatureThe mixture was cooled
- filtrationfiltered
- concentrationThe filtrate was concentrated
- distillationthe resulting residue was distilled
出典と根拠
- ORDレコード
- ord-90919a21f3e44b4aa4b27f128eb16600
- 出典データセット
- uspto-grants-1980_09
- 特許番号
- US04221716
反応ノート
読み込み中…