Diazomethane → Methyl 2-(2-bromoethyl)benzoate
反応式
[Br:1][CH2:2][CH2:3][C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([OH:8])=[O:7].[N+](=[CH2:15])=[N-]>CCOCC>[Br:1][CH2:2][CH2:3][C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([O:8][CH3:15])=[O:7]参加物
4
実験手順
2-(2-Bromoethyl)-benzoic acid (11.4 g, 50 mmol) is added to a solution of diazomethan in ether at 0° C. The reaction mixture is concentrated in vacuo, and the residue purified by chromatography to give the desired compound as a colourless oil.
後処理
- concentrationThe reaction mixture is concentrated in vacuo
- customthe residue purified by chromatography
出典と根拠
- ORDレコード
- ord-da5ac1400293420aaaabc1b65bdad173
- 出典データセット
- uspto-grants-1995_02
- 特許番号
- US05387582
反応ノート
読み込み中…