2-(Bis(methylsulfanyl)methylidene)propanedinitrile → HCID 178503874、化合物

HRID 27383

反応式

HRID 27383 の反応式
CS[C:3](=[C:6]([C:9]#[N:10])[C:7]#[N:8])[S:4][CH3:5].[CH3:11][C:12]1[N:13]=[CH:14][NH:15][C:16]=1[CH2:17][S:18][CH2:19][CH2:20][NH2:21]>C(O)C>[C:9]([C:6]([C:7]#[N:8])=[C:3]([S:4][CH3:5])[NH:21][CH2:20][CH2:19][S:18][CH2:17][C:16]1[NH:15][CH:14]=[N:13][C:12]=1[CH3:11])#[N:10]

参加物

4

反応物 2

HCID 992292-(Bis(methylsulfanyl)methylidene)propanedinitrileHCID 178433288HCID 178433288、化合物

生成物 1

HCID 178503874HCID 178503874、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Bis(methylthio)methylenemalononitrile [prepared according to the procedure described in Chem. Ber., 95, 2861 (1962)] (9.94 g, 58.4 mmole) was added with stirring to a solution of 2-[(4-methyl-1H-imidazol-5-yl)methylthio]ethylamine (10.0 g, 58.4 mmole) in 100 ml of absolute ethanol. After stirring at room temperature for 90 minutes, the solvent was removed by evaporation under reduced pressure, and the residue placed on silica gel and chromatographed to yield the title compound (15.65 g).

後処理

  1. addition, 95, 2861 (1962)] (9.94 g, 58.4 mmole) was added
  2. customthe solvent was removed by evaporation under reduced pressure
  3. customchromatographed

出典と根拠

ORDレコード
ord-a4e77f421a5f455b87c2ea3e368dae3d
出典データセット
uspto-grants-1980_09
特許番号
US04221737

関連ノート

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