1,4-Naphthoquinone → HCID 14614968、化合物

HRID 273910ノート

反応式

HRID 273910 の反応式
[C:1]1(=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:11])[CH:3]=[CH:2]1.[CH:13]([NH:17][C:18](=[O:27])[O:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[CH:14][CH:15]=[CH2:16]>C1(C)C=CC=CC=1.C1(C=CC(O)=CC=1)O>[CH2:20]([O:19][C:18]([NH:17][CH:13]1[CH:2]2[CH:3]([C:4](=[O:11])[C:5]3[C:10]([C:1]2=[O:12])=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH2:16][CH:15]=[CH:14]1)=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

参加物

5

反応物 2

HCID 85301,4-NaphthoquinoneHCID 329894HCID 329894、化合物

生成物 1

HCID 14614968HCID 14614968、化合物収率 98.6%

試薬・触媒・溶媒 2

HCID 785Hydroquinone触媒HCID 1140Toluene溶媒

反応条件

温度
25 °C

実験手順

3.16 g of 1,4-naphthoquinone, 4.48 g of benzyl N-butadienylcarbamate and 50 mg of hydroquinone were dissolved in 100 ml of toluene and stirred at 25° C. for 8 hours and the solution was then concentrated in vacuo. The residue was taken up in chloroform, the solution was filtered through silica gel and the filtrate was concentrated in vacuo. 7.12 g of 1-benzyloxycarbonylamino-1,4,4a,9a-tetrahydroanthraquinone (93% pure; 92% of theory) were obtained.

後処理

  1. concentrationthe solution was then concentrated in vacuo
  2. filtrationthe solution was filtered through silica gel
  3. concentrationthe filtrate was concentrated in vacuo

出典と根拠

ORDレコード
ord-be620bcbb5b1487b9e47685ab899461e
出典データセット
uspto-grants-1995_02
特許番号
US05387704

反応ノート

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