2,6-Dimethylquinoline → 4-[2,6-Dimethyl-1quinolinio]butanesulfonate

HRID 274200

反応式

HRID 274200 の反応式
[CH3:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH3:12])[CH:8]=2)[N:3]=1.[CH2:13]1[S:18](=[O:20])(=[O:19])[O:17][CH2:16][CH2:15][CH2:14]1>CC(C)=O>[CH3:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH3:12])[CH:8]=2)[N+:3]=1[CH2:16][CH2:15][CH2:14][CH2:13][S:18]([O-:20])(=[O:19])=[O:17]

参加物

4

反応物 2

HCID 134142,6-DimethylquinolineHCID 154111,4-Butane sultone

生成物 1

HCID 867484494-[2,6-Dimethyl-1quinolinio]butanesulfonate収率 94.3%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

72.3 g (0.46 mol) of 2,6-dimethylquinoline and 188 g (1.4 mol) of butanesultone were heated at 145° C. for 4 hours with stirring. After being cooled to room temperature, 500 ml of acetone was added to the reaction mixture, which was cooled with ice for 30 minutes for crystallization. The crystals formed were filtered out, washed with acetone and dried to obtain 127.3 g of 4-[2,6-dimethyl-1quinolinio]butanesulfonate. The yield of the product was 94%.

後処理

  1. temperaturewas cooled with ice for 30 minutes for crystallization
  2. customThe crystals formed
  3. filtrationwere filtered out
  4. washwashed with acetone
  5. customdried

出典と根拠

ORDレコード
ord-264c39146dce4d0d9cbf716bd916f9ed
出典データセット
uspto-grants-1995_02
特許番号
US05389505

関連ノート

読み込み中…