6-Chloro-2,7-dimethyl[1,2,4]triazolo[1,5-b]pyridazine → 1-Butanesulfonamide, 2-(((2,7-dimethyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)methyl)-2-methyl-

HRID 274280ノート

反応式

HRID 274280 の反応式
CN(C=[N:5][S:6]([CH2:9][C:10]([CH2:14][CH3:15])([CH3:13])[CH2:11][OH:12])(=[O:8])=[O:7])C.Cl[C:17]1[C:18]([CH3:27])=[CH:19][C:20]2[N:21]([N:23]=[C:24]([CH3:26])[N:25]=2)[N:22]=1>>[CH2:14]([C:10]([CH3:13])([CH2:9][S:6](=[O:7])(=[O:8])[NH2:5])[CH2:11][O:12][C:17]1[C:18]([CH3:27])=[CH:19][C:20]2[N:21]([N:23]=[C:24]([CH3:26])[N:25]=2)[N:22]=1)[CH3:15]

参加物

3

反応物 2

HCID 107261326-Chloro-2,7-dimethyl[1,2,4]triazolo[1,5-b]pyridazineHCID 544433203-(N,N-dimethylaminomethylene)aminosulfonyl-2-ethyl-2-methyl-1-propanol

生成物 1

HCID 30737991-Butanesulfonamide, 2-(((2,7-dimethyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)methyl)-2-methyl-

実験手順

Using 3-(N,N-dimethylaminomethylene)aminosulfonyl-2-ethyl-2-methyl-1-propanol and 6-chloro-2,7-dimethyl[1,2,4]triazolo[1,5-b]pyridazine, the same reaction as in Example 6 was conducted to produce the title compound. m.p. 194°-195° C.

後処理

  1. customthe same reaction as in Example 6

出典と根拠

ORDレコード
ord-2110b5f2589f44628cbf239c8776778d
出典データセット
uspto-grants-1995_02
特許番号
US05389633

反応ノート

読み込み中…