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Thiosemicarbazide → 5-(2-amino-6H-1,3,4-thiadiazin-5-yl)-3-nitropyrocatechol hydrobromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thiosemicarbazide | HCID 2723789 | — |
| 反応物 | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| 溶媒 | 1-Butanol | HCID 263 | — |
| 生成物 | 5-(2-amino-6H-1,3,4-thiadiazin-5-yl)-3-nitropyrocatechol hydrobromide | HCID 135665327 | — |
反応手順
A solution of 1.38 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone and 461 mg of thiosemicarbazide in 20 ml of n-butanol is heated to boiling under reflux for 60 minutes. After cooling to room temperature the crystals are filtered under suction and recrystallized from n-butanol. There is obtained 5-(2-amino-6H-1,3,4-thiadiazin-5-yl)-3-nitropyrocatechol hydrobromide of m.p. 265°-267°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05389653 |
| 出典データセット | uspto-grants-1995_02 |
| ORD ID | ord-2e434c7299e3461bb2b24c3e639093e1 |
| 出典メモ | uspto-grants-1995_02 |