N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy]acetamidine → 5-(3,4-Dimethoxy-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole

HRID 274548

反応式

HRID 274548 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:13]=[C:14]([N+:18]([O-:20])=[O:19])[C:15]=1[O:16][CH3:17])[C:6]([O:8][N:9]=[C:10]([NH2:12])[CH3:11])=O>C(O)(=O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:6]2[O:8][N:9]=[C:10]([CH3:11])[N:12]=2)[CH:13]=[C:14]([N+:18]([O-:20])=[O:19])[C:15]=1[O:16][CH3:17]

参加物

3

反応物 1

HCID 53789064N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy]acetamidine

生成物 1

HCID 214590805-(3,4-Dimethoxy-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

2.0 g of N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy]acetamidine are held at reflux temperature for 1 hour in 20 ml of glacial acetic acid. After distillation of the acetic acid, the crystalline residue is recrystallized from ether/hexane. There is obtained 5-(3,4-dimethoxy-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole in the form of colorless crystals of m.p. 111°.

後処理

  1. distillationAfter distillation of the acetic acid
  2. customthe crystalline residue is recrystallized from ether/hexane

出典と根拠

ORDレコード
ord-acb8a08e28d44815803c469e8ffccd6f
出典データセット
uspto-grants-1995_02
特許番号
US05389653

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