Ammonia → 4-cyano-1H-pyrrole-2-carboxamide
反応式
ClC(Cl)(Cl)[C:3]([C:5]1[NH:6][CH:7]=[C:8]([C:10]#[N:11])[CH:9]=1)=[O:4].[NH3:14]>CO.O>[C:10]([C:8]1[CH:9]=[C:5]([C:3]([NH2:14])=[O:4])[NH:6][CH:7]=1)#[N:11]参加物
5
実験手順
A solution of 2-trichloroacetylpyrrole-4-carbonitrile (20 g, 84.2 mmol) in methanol is treated with ammonia (51 mL), stirred at room temperature for 30 minutes and diluted with water. The aqueous mixture is filtered to obtain the title product as a white solid (7.0 g, mp 253°-256° C.).
後処理
- filtrationThe aqueous mixture is filtered
出典と根拠
- ORDレコード
- ord-d13606e42b364f86abc512497f317646
- 出典データセット
- uspto-grants-1995_02
- 特許番号
- US05389669
反応ノート
読み込み中…