化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuryl chloride → Ethyl 2-chloro-3-oxopentanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuryl chloride | HCID 24648 | — |
| 反応物 | Ethyl 3-oxovalerate | HCID 78656 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | Ethyl 2-chloro-3-oxopentanoate | HCID 12923424 | — |
反応手順
Sulphuryl chloride (286 g.) was added dropwise to a solution of ethyl 3-oxopentanoate (300 g.) in chloroform (250 ml.) at 10°-15°. Following addition the mixture was stirred overnight at room temperature, heated under reflux for 0.5 hour and cooled. After washing with water, sodium bicarbonate and water, the solution was dried (sodium sulphate), concentrated, and fractionated to yield ethyl 2-chloro-3-oxopentanoate, b.p. 94°-96°/14 mm.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04221802 |
| 出典データセット | uspto-grants-1980_09 |
| ORD ID | ord-4bf2e9ed074343889166e28dfcebce1b |
| 出典メモ | uspto-grants-1980_09 |