Ethyl isobutyrylacetate → HCID 178472908、化合物
反応式
[N:1]([O-:3])=O.[Na+].[C:5]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])(=[O:9])[CH:6]([CH3:8])[CH3:7]>O.C(O)(=O)C>[N:1](=[C:10]([C:5](=[O:9])[CH:6]([CH3:8])[CH3:7])[C:11]([O:13][CH2:14][CH3:15])=[O:12])[OH:3]参加物
5
実験手順
A solution of sodium nitrite (43.8 g.) in water (92 ml.) was added dropwise, with stirring, to a solution of ethyl isobutyrylacetate (100.3 g.) in acetic acid (80 ml.) at 0°. After stirring at 0° for 30 minutes then at room temperature for 3 hours, water (100 ml.) was added and the mixture extracted with ether. The extracts were washed with water, saturated sodium bicarbonate solution and water. After drying (CaSO4), the solution was evaporated to give ethyl 2-oximino-4-methyl-3-oxopentanoate (112 g.) as a crude oil.
後処理
- waitat room temperature for 3 hours
- extractionthe mixture extracted with ether
- washThe extracts were washed with water, saturated sodium bicarbonate solution and water
- dry with materialAfter drying (CaSO4)
- customthe solution was evaporated
出典と根拠
- ORDレコード
- ord-f145599472d64714b63d867f63d5bcac
- 出典データセット
- uspto-grants-1980_09
- 特許番号
- US04221802
反応ノート
読み込み中…