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Diethylformamide → 2-Amino-6-chloropurine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethylformamide | HCID 12051 | — |
| 反応物 | 1-Piperidinecarboxaldehyde | HCID 17429 | — |
| 反応物 | 2-Diethylaminomethyleneamino-6-chloropurine | HCID 53860168 | — |
| 反応物 | 2-Piperidinomethyleneamino-6-chloropurine | HCID 53979998 | — |
| 生成物 | 2-Amino-6-chloropurine | HCID 5360349 | — |
反応手順
The reaction is carried out in the same manner as in Example 2 except that N,N-diethylformamide or N-formylpiperidine is used in the place of N,N-dimethylformamide to yield, respectively, a crystal of 2-diethylaminomethyleneamino-6-chloropurine or 2-piperidinomethyleneamino-6-chloropurine as an intermediate for further synthesis. A further treatment is carried out in the same manner as in Example 2 on these crystals to yield a white crystal of 2-amino-6-chloropurine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05391733 |
| 出典データセット | uspto-grants-1995_02 |
| ORD ID | ord-f8efbab678334a79b2529d4e996099eb |
| 出典メモ | uspto-grants-1995_02 |