化工社化工社 化学情報印刷レポート · 研究参考用
Triethyl Citrate → 2-(Oxolan-3-yl)ethan-1-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethyl Citrate | HCID 6506 | — |
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | (Oxan-4-yl)methanol | HCID 2773573 | 3.6% |
| 生成物 | 2-(Oxolan-3-yl)ethan-1-ol | HCID 11126225 | 49% |
反応手順
400 ml of triethyl citrate were hydrogenated at 225° C. and 200 bar together with 1100 ml of tetrahydrofuran and 60 g of catalyst H (3-mm tablets) until the take-up of hydrogen had ceased. The reaction product was freed from tetrahydrofuran and ethanol and distilled under reduced pressure, giving 93.6 g (49%) of 3-(2'-hydroxyethyl)tetrahydrofuran and 6.8 g (3.6%) of 4-hydroxymethyltetrahydropyran.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05391771 |
| 出典データセット | uspto-grants-1995_02 |
| ORD ID | ord-e0c800179a6a41f3800b0b39c6564e34 |
| 出典メモ | uspto-grants-1995_02 |