Ethylenediamine → N-(2-thiazolylmethyl)ethylenediamine
反応式
[CH2:1]([NH2:4])[CH2:2][NH2:3].Cl[CH2:6][C:7]1[S:8][CH:9]=[CH:10][N:11]=1>>[S:8]1[CH:9]=[CH:10][N:11]=[C:7]1[CH2:6][NH:3][CH2:2][CH2:1][NH2:4]参加物
3
実験手順
Reacting ethylenediamine with 2-chloromethylthiazole by the procedure of Example 34 gives N-(2-thiazolylmethyl)ethylenediamine. Reacting this intermediate with S-methyl-N-nitroisothiourea by the procedure of Example 2(ii) gives N-nitro-N'-[2-(2-thiazolylmethylamino)ethyl]guanidine. Treatment with hydrobromic acid gives the hydrobromide salt.
出典と根拠
- ORDレコード
- ord-a5ea7c75d0d74eaa9dac82167c52a3aa
- 出典データセット
- uspto-grants-1980_09
- 特許番号
- US04221802
反応ノート
読み込み中…