反応式
[CH3:1][O:2][C:3]1[C:11]2[NH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[N:8][C:7]=2[CH:6]=[CH:5][CH:4]=1.[CH2:16](Br)[CH2:17][CH3:18]>>[CH3:1][O:2][C:3]1[C:11]2[N:10]=[C:9]([C:12]([F:15])([F:13])[F:14])[N:8]([CH2:16][CH2:17][CH3:18])[C:7]=2[CH:6]=[CH:5][CH:4]=1参加物
3
実験手順
Prepared from 4-methoxy-2-trifluoromethylbenzimidazole (2.4 g) and propyl bromide (3.02 ml). Purification by flash chromatography on silica eluting with 15% ethyl acetate in hexane gave the title compound as a white solid (2.03 g).
後処理
- customPurification by flash chromatography on silica eluting with 15% ethyl acetate in hexane
出典と根拠
- ORDレコード
- ord-3768b69c0a5644d48eb12c0816af51a4
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06353010B1
関連ノート
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