Water → 2-Ethylbenzo[d]oxazol-4-ol

HRID 275797

反応式

HRID 275797 の反応式
Cl.[NH2:2][C:3]1[C:9]([OH:10])=[CH:8][CH:7]=[CH:6][C:4]=1[OH:5].C(O[C:14](OCC)(OCC)[CH2:15][CH3:16])C.O>C(O)C>[CH2:15]([C:16]1[O:5][C:4]2[CH:6]=[CH:7][CH:8]=[C:9]([OH:10])[C:3]=2[N:2]=1)[CH3:14]

参加物

5

反応物 3

HCID 962WaterHCID 66995Ethyl orthopropionateHCID 4592471,3-Benzenediol, 2-amino-, hydrochloride (1:1)

生成物 1

HCID 156656802-Ethylbenzo[d]oxazol-4-ol

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
150 °C

実験手順

A mixture of 2-aminoresorcinol hydrochloride (5.0 g) and triethylorthopropionate (13.7 ml) was heated to 150° C. for 2 h before being poured into a mixture of water (140 ml) and ethanol (35 ml). The mixture was stirred vigorously for 30 minutes at room temperature. The resulting precipitate was removed by filtration and dried to give the title compound as a beige solid (4.11 g).

後処理

  1. customThe resulting precipitate was removed by filtration
  2. customdried

出典と根拠

ORDレコード
ord-431cdd863f2841b39b43c21f7b1cdf97
出典データセット
uspto-grants-2002_03
特許番号
US06353010B1

関連ノート

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