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5-Chlorothieno[3,2-b]pyridine-2-sulfonyl chloride → 5-Chlorothieno[3,2-b]pyridine-2-sulfonic acid [1-(3-cyanobenzyl)-2-oxo-pyrrolidin-3-(S)-yl]-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Chlorothieno[3,2-b]pyridine-2-sulfonyl chloride | HCID 22017299 | — |
| 反応物 | 3-(3-(S)-Amino-2-oxopyrrolidin-1-ylmethyl)benzonitrile hydrochloride | HCID 22870786 | — |
| 生成物 | 5-Chlorothieno[3,2-b]pyridine-2-sulfonic acid [1-(3-cyanobenzyl)-2-oxo-pyrrolidin-3-(S)-yl]-amide | HCID 54313365 | — |
反応手順
The title compound is prepared from 3-(3-(S)-amino-2-oxo-pyrrolidin-1-ylmethyl)-benzonitrile hydrochloride as described in EXAMPLE 1, Part E using 5-chlorothieno[3,2-b]pyridine-2-sulfonyl chloride in place of benzo[b]thiophene-2sulfonyl chloride. The product is obtained as a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731315 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-e0b43900a7e1454399672e06b3cc15d4 |
| 出典メモ | uspto-grants-1998_03 |