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Bromine → HCID 20287115、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | Methyl 5-acetyl-2-methoxybenzoate | HCID 606426 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | HCID 20287115 | HCID 20287115 | 75.4% |
反応手順
To a solution of 52.0 g (0.25 mole) of this ketone in 400 ml of chloroform is added a solution of 40.0 g (0.25 mole) of bromine in 200 ml of chloroform at such a rate as reaction mixture decolorizes (50 minutes after a 25 minute initiation period). Solvent is evaporated and the residue recrystallized from methanol to give 54.1 g (75%) of methyl 5-(2-bromoacetyl)-2-methoxybenzoate, m.p. 149°-153° C. A second crop of 10.4 g is obtained from the mother liquor.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04221808 |
| 出典データセット | uspto-grants-1980_09 |
| ORD ID | ord-c36183a7d8af4e76bb9decf1a4cd7b2b |
| 出典メモ | uspto-grants-1980_09 |