関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Isobutylamine | HCID 6558 | — |
| 反応物 | 2-(Phenylmethyl)oxirane | HCID 94826 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1-(Isobutylamino)-3-phenylpropan-2-ol | HCID 412096 | 42.1% |
反応手順
2,3-Epoxypropyl benzene (10 g, 74.5 mmol) and isobutylamine (5.4 g, 74.5 mmol) were mixed then treated with water (2 mL). The mixture was stirred overnight at 110° C., then distilled to yield N-(3-phenyl-2-hydroxypropyl)N-isobutylamine (6.5 g): bp 115-117° C. (1 mmHg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06353006B1 |
|---|
| 出典データセット | uspto-grants-2002_03 |
|---|
| ORD ID | ord-38e71653d71648c093523f85378accd1 |
|---|
| 出典メモ | uspto-grants-2002_03 |
|---|
