1,2-Dichloro-4-isothiocyanatobenzene → 2-(3,4-Dichlorophenylimino)-3-(cyclopropylmethyl)-1,3-thiazolidine
反応式
[Cl-].[CH:2]1([CH2:5][NH2+:6][CH2:7][CH2:8]Cl)[CH2:4][CH2:3]1.[Cl:10][C:11]1[CH:12]=[C:13]([N:18]=[C:19]=[S:20])[CH:14]=[CH:15][C:16]=1[Cl:17]>>[Cl:10][C:11]1[CH:12]=[C:13]([N:18]=[C:19]2[N:6]([CH2:5][CH:2]3[CH2:3][CH2:4]3)[CH2:7][CH2:8][S:20]2)[CH:14]=[CH:15][C:16]=1[Cl:17]参加物
3
実験手順
2-Hydroxyethylamine was reacted with cyclopropylmethyl bromide according to Method B2a to give N-cyclopropylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cyclopropylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 3,4-dichlorophenyl isothiocyanate to give 2-(3,4-dichlorophenylimino)-3-(cyclopropylmethyl)-1,3-thiazolidine.
出典と根拠
- ORDレコード
- ord-78ba16647dc24a13b0dfdd6063be108a
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06353006B1
反応ノート
読み込み中…