1,2-Dichloro-4-isothiocyanatobenzene → 2-(3,4-Dichlorophenylimino)-3-(cyclobutylmethyl)-1,3-thiazolidine
反応式
[Cl-].[CH:2]1([CH2:6][NH2+:7][CH2:8][CH2:9]Cl)[CH2:5][CH2:4][CH2:3]1.[Cl:11][C:12]1[CH:13]=[C:14]([N:19]=[C:20]=[S:21])[CH:15]=[CH:16][C:17]=1[Cl:18]>>[Cl:11][C:12]1[CH:13]=[C:14]([N:19]=[C:20]2[N:7]([CH2:6][CH:2]3[CH2:3][CH2:4][CH2:5]3)[CH2:8][CH2:9][S:21]2)[CH:15]=[CH:16][C:17]=1[Cl:18]参加物
3
実験手順
2-Hydroxyethylamine was reacted with cyclobutylmethyl bromide according to Method B2a to give N-cyclobutylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cyclobutylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 3,4-dichlorophenyl isothiocyanate to give 2-(3,4-dichlorophenylimino)-3-(cyclobutylmethyl)-1,3-thiazolidine.
出典と根拠
- ORDレコード
- ord-cfd7ff92352e4f07a34b7f9d8114bc0c
- 出典データセット
- uspto-grants-2002_03