化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → N-(4-chlorobenzyl)-N-(2-chloroethyl)ammonium chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2-(4-Chloro-benzylamino)-ethanol | HCID 424452 | — |
| 生成物 | N-(4-chlorobenzyl)-N-(2-chloroethyl)ammonium chloride | HCID 18316438 | — |
反応手順
2-Hydroxyethylamine was reacted with 4-chlorobenzyl bromide according to Method B2a to give N-(4-chlorobenzyl)-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-(4-chlorobenzyl)-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 4-cyano-2-ethylphenyl isothiocyanate to give 2-(4-cyano-2-ethylphenylimino)-3-(4-chlorobenzyl)-1,3-thiazolidine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06353006B1 |
| 出典データセット | uspto-grants-2002_03 |
| ORD ID | ord-468de80c31c845ff825867ac8d9b3b8e |
| 出典メモ | uspto-grants-2002_03 |