化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → 3-[(4-Nitrophenyl)sulfonyl]aminophenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | 4-Nitrobenzenesulfonyl chloride | HCID 7404 | — |
| 反応物 | 3-Aminophenol | HCID 11568 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 3-[(4-Nitrophenyl)sulfonyl]aminophenol | HCID 22372349 | 56.6% |
反応手順
A mixture of 3-aminophenol (33 g, 0.3 mole) and p-nitrobenzenesulfonyl chloride (66 g, 0.3 mole) in pyridine (350 ml) was heated at 80° on a steam bath for 4 hours. The reaction mixture was poured on ice and acidified with acetic acid. The precipitated product was filtered and recrystallized from isopropanol and gave 50 g (49%) of product which was used in Part B.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04222948 |
| 出典データセット | uspto-grants-1980_09 |
| ORD ID | ord-26a0e1480bfd42aead7188fc89038f4e |
| 出典メモ | uspto-grants-1980_09 |