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Bromocycloheptane → 2-(2-Methyl-4-nitrophenylimino)-1-cycloheptyl-3-thia-1-azaspiro[4.4]nonane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromocycloheptane | HCID 16992 | — |
| 反応物 | 2-(2-Methyl-4-nitrophenylimino)-3-thia-1-azaspiro[4.4]nonane | HCID 178428736 | — |
| 生成物 | 2-(2-Methyl-4-nitrophenylimino)-1-cycloheptyl-3-thia-1-azaspiro[4.4]nonane | HCID 22951254 | — |
反応手順
1-Hydroxymethylcyclopentanamine was prepared according to Method B1c. The 2-hydroxyethylamine was sequentially reacted with SOCl2 and 2-methyl-4-nitrophenyl isothiocyanate according to Method C2a to give 2-(2-methyl-4-nitrophenylimino)-3-thia-1-azaspiro[4.4]nonane. The thiazolidine was reacted with cycloheptyl bromide according to Method D2e to give 2-(2-methyl-4-nitrophenylimino)-1-cycloheptyl-3-thia-1-azaspiro [4.4]nonane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06353006B1 |
| 出典データセット | uspto-grants-2002_03 |
| ORD ID | ord-5948220c499f40c380bccbb8edcc1b60 |
| 出典メモ | uspto-grants-2002_03 |