化工社化工社 化学情報印刷レポート · 研究参考用
Cyclohexanecarboxylic acid → N-(5-Phenylthiophen-2-yl)cyclohexanecarboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclohexanecarboxylic acid | HCID 7413 | — |
| 反応物 | N-(3-carboxy-methyl-5-phenyl-2-thienyl)-cyclohexane carboxamide | HCID 70592634 | — |
| 反応物 | HCID 178526965 | HCID 178526965 | — |
| 溶媒 | 2,4,6-Trimethylpyridine | HCID 7953 | — |
| 生成物 | N-(5-Phenylthiophen-2-yl)cyclohexanecarboxamide | HCID 23341601 | — |
反応手順
This compound (m.p. 174° C.) was prepared from N-(3-carboxy-methyl-5-phenyl-2-thienyl)-cyclohexane carboxamide (31.1 g, 0.1 mole) and LiI.2H2O (48.1 g, 0.32 mole) by refluxing in collidine (125 ml.) according to the procedure of Example 53 (a). This compound was also prepared according to the procedure of Example 53(b), using cyclohexane carboxylic acid as the acylating agent. The products of the two processes were spectrally identical and had a melting point of 175° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04222946 |
| 出典データセット | uspto-grants-1980_09 |
| ORD ID | ord-fa69975da3e14d579e8308f5c3d04eb7 |
| 出典メモ | uspto-grants-1980_09 |