Chloroacetic Acid → 2-(2-Methyl-4-nitrophenylimino)-3-(1-cyclohexylethyl)-1,3-thiazolidin-4-one

反応式

[CH3:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[N:11]=[C:12]=[S:13].[NH2:14][CH:15]([CH:17]1[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1)[CH3:16].Cl[CH2:24][C:25](O)=[O:26]>>[CH3:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[N:11]=[C:12]1[N:14]([CH:15]([CH:17]2[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]2)[CH3:16])[C:25](=[O:26])[CH2:24][S:13]1

参加物

反応物 3

HCID 300Chloroacetic Acid

HCID 1107331-Cyclohexylethylamine

HCID 1456212-Methyl-4-nitrophenyl isothiocyanate

生成物 1

HCID 183160842-(2-Methyl-4-nitrophenylimino)-3-(1-cyclohexylethyl)-1,3-thiazolidin-4-one

実験手順

2-Methyl-4-nitrophenyl isothiocyanate was reacted with I -amino-1-cyclohexylethane followed by chloroacetic acid according to Method C8a to afford 2-(2-methyl-4-nitrophenylimino)-3-(1-cyclohexylethyl)-1,3-thiazolidin4-one.

出典と根拠

ORDレコード: ord-2a8a108c243840d486ebfa93636a1d98
出典データセット: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06353006B1

反応ノート

読み込み中…