Benzene → HCID 11252129、化合物
反応式
[CH3:1]/[C:2](/[CH2:8][CH2:9][CH2:10][C:11]([CH3:13])=[CH2:12])=[CH:3]\[C:4](OC)=[O:5].C1C=CC=CC=1.[H-].C([Al+]CC(C)C)C(C)C.Cl>CO>[CH3:1]/[C:2](/[CH2:8][CH2:9][CH2:10][C:11]([CH3:13])=[CH2:12])=[CH:3]\[CH2:4][OH:5]参加物
6
実験手順
To a mixture of the foregoing dienoic ester (0.827 mmol) and 7.5 ml of benzene, under nitrogen, is added 1.5 ml of 1.78 M diisobutyl aluminum hydride (DIBAH). After about 2 hours, 1 ml more of DIBAH is added and the reaction continued to completion as checked by thin layer chromatography. The reaction is worked up by adding about 2 ml of methanol and dilute HCl. The aqueous layer is extracted with ether. Then the combined ether phases are washed with water and brine, dried over sodium sulfate and solvent evaporated to yield (E)-3,7-dimethyl-2,7-octadien-1-ol.
後処理
- extractionThe aqueous layer is extracted with ether
- washThen the combined ether phases are washed with water and brine
- dry with materialdried over sodium sulfate and solvent
- customevaporated
出典と根拠
- ORDレコード
- ord-b9be3fd8cdfe4b6893265cf7461cd854
- 出典データセット
- uspto-grants-1980_09
- 特許番号
- US04223012
反応ノート
読み込み中…