Ethyl cyanoacetate → ethyl 5-amino-1-p-tolyl-1H-1,2,3-triazole-4-carboxylate

関与物質

役割	名称	HCID	仕込み量
反応物	Ethyl cyanoacetate	HCID 7764	—
反応物	1-Azido-4-methylbenzene	HCID 137430	—
溶媒	Ethanol	HCID 702	—
生成物	ethyl 5-amino-1-p-tolyl-1H-1,2,3-triazole-4-carboxylate	HCID 12699267	74%

反応手順

Reaction of p-tolyl azide (9.38 g; 0.0705 mole) with ethyl cyanoacetate (7.96 g: 0.0705 mole) as described in example 1a gave 12.76 g (74%) of the triazole of mp (EtOH) 152-153° C. (lit mp 147.5° C., B. R. Brown, D. L. Hammick and S. G. Heritage J. Chem. Soc. 3870 [1953]). (Found; C, 58.38; H 5.90; N, 22.89; C12H14N4O2 requires; C, 58.52; H, 5.73; N, 22.75%).

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US04223032
出典データセット	uspto-grants-1980_09
ORD ID	ord-c46b9c2f3e4f410c85dd4d7b9191d154
出典メモ	uspto-grants-1980_09