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5-Methylthiophene-2-carbohydrazide → 5-Methyl-thiophen-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Methylthiophene-2-carbohydrazide | HCID 2760085 | — |
| 反応物 | 2-(Phenylsulfonyl)-ethanimidic acid ethyl ester | HCID 70089442 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 5-Methyl-thiophen-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide | HCID 70090576 | 91.2% |
反応手順
1.75 g (0.0077 Mol) of 2-(phenylsulfonyl)-ethanimidic acid ethyl ester was stirred together with 1.2 g (0.0077 mol) 5-methyl-thiophen-2-carboxylic acid hydrazide in 14 ml chloroform for 24 hours at 50° C. The resulting precipitate was filtered off and dried. 2.37 g of 5-methyl-thiophen-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide was obtained as off-white crystals. Mp.: 222° C. (dec.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06355653B1 |
| 出典データセット | uspto-grants-2002_03 |
| ORD ID | ord-320543ae4d58441c90f95b881d746d71 |
| 出典メモ | uspto-grants-2002_03 |