Pyridine-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide → HCID 178527399、化合物

HRID 277031ノート

反応式

HRID 277031 の反応式
[NH2:1][C:2](=[N:13][NH:14][C:15]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1)=O)[CH2:3][S:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)(=[O:6])=[O:5]>C(O)C>[C:7]1([S:4]([CH2:3][C:2]2[N:1]=[C:15]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=3)[NH:14][N:13]=2)(=[O:6])=[O:5])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

参加物

3

反応物 1

HCID 86757847Pyridine-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide

生成物 1

HCID 178527399HCID 178527399、化合物収率 84%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

7.70 g (0.025 mol) Pyridine-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide were heated at 200° C. for 20 minutes. The molten mass was then cooled, dissolved in 30 ml hot ethanol and stirred for two hous at room temperature. The precipitated crystals were filtered off and dried to yield 6.22 g (84%) 3-benzenesulfonylmethyl-5-pyridin-2-yl-1H-[1,2,4]triazole. MS m/e (%): 300 (M+, 100).

後処理

  1. temperatureThe molten mass was then cooled
  2. filtrationThe precipitated crystals were filtered off
  3. customdried

出典と根拠

ORDレコード
ord-46c51b5e570049dc992379bbc547c901
出典データセット
uspto-grants-2002_03
特許番号
US06355653B1

反応ノート

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