Benzenecarboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide → 3-benzenesulfonylmethyl-5-phenyl-1H-[1,2,4]triazole
反応式
[NH2:1][C:2](=[N:13][NH:14][C:15]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=O)[CH2:3][S:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)(=[O:6])=[O:5]>C(O)C>[C:7]1([S:4]([CH2:3][C:2]2[N:1]=[C:15]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[NH:14][N:13]=2)(=[O:6])=[O:5])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1参加物
3
実験手順
93.1 g (0.29 mol) Benzenecarboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide were heated at 200° C. for 30 minutes. The molten mass was then cooled, dissolved in 500 ml hot ethanol and stirred for 15 hous at room temperature. The precipitated crystals were filtered off and dried to yield 65.6 g (75%) 3-benzenesulfonylmethyl-5-phenyl-1H-[1,2,4]triazole with mp. 141-144° C. MS m/e (%): 299 (M+, 100).
後処理
- temperatureThe molten mass was then cooled