(Z)-3-(2-methyl-pyridin-4-yl)-acrylonitrile → 7-(2-Methyl-pyridin-4-yl)-2-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277108ノート

反応式

HRID 277108 の反応式
C1(S([CH2:10][C:11]2[N:12]=[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)[NH:14][N:15]=2)(=O)=O)C=CC=CC=1.[CH3:22][C:23]1[CH:28]=[C:27](/[CH:29]=[CH:30]\[C:31]#[N:32])[CH:26]=[CH:25][N:24]=1>>[CH3:22][C:23]1[CH:28]=[C:27]([C:29]2[CH:30]=[C:31]([NH2:32])[N:15]3[N:14]=[C:13]([C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=4)[N:12]=[C:11]3[CH:10]=2)[CH:26]=[CH:25][N:24]=1

参加物

3

反応物 2

HCID 86757851(Z)-3-(2-methyl-pyridin-4-yl)-acrylonitrileHCID 178527399HCID 178527399、化合物

生成物 1

HCID 226296537-(2-Methyl-pyridin-4-yl)-2-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

実験手順

The title compound, MS m/e (%):303 (M+H+,100), was prepared in accordance with the general method of example 1 from 2-(5-benzenesulfonylmethyl-2H-[1,2,4]triazol-3-yl)-pyridine and (E)/(Z)-3-(2-methyl-pyridin-4-yl)-acrylonitrile.

出典と根拠

ORDレコード
ord-9f698d31f800447ab5d66f0f4db39ea6
出典データセット
uspto-grants-2002_03
特許番号
US06355653B1

反応ノート

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