1,8-Diazabicyclo(5.4.0)undec-7-ene → 2-(2-Methyl-imidazol-1-yl)-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277124ノート

反応式

HRID 277124 の反応式
CS([C:4]1[N:19]=[C:7]2[CH:8]=[C:9]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)[CH:10]=[C:11]([NH2:12])[N:6]2[N:5]=1)=O.[N:20]12[CH2:30][CH2:29]C[N:27]=[C:26]1[CH2:25]CCCC2>CC1NC=CN=1>[CH3:25][C:26]1[N:20]([C:4]2[N:19]=[C:7]3[CH:8]=[C:9]([C:13]4[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=4)[CH:10]=[C:11]([NH2:12])[N:6]3[N:5]=2)[CH:30]=[CH:29][N:27]=1

参加物

4

反応物 2

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 226297032-Methanesulfinyl-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

生成物 1

HCID 183136602-(2-Methyl-imidazol-1-yl)-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

試薬・触媒・溶媒 1

HCID 127492-Methylimidazole溶媒

実験手順

The title compound, MS m/e (%):292 (M+H+,100), was prepared in accordance with the method of example 339b) from 2-methanesulfinyl-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine and 1,8-diazabicyclo[5.4.0]undec-7-en in 2-methylimidazole at 170° C.

出典と根拠

ORDレコード
ord-6bfe6746b57c4ed5bae45fa92cce01fc
出典データセット
uspto-grants-2002_03
特許番号
US06355653B1

反応ノート

読み込み中…