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Triethylamine → HCID 22625376、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | ((p-(Benzyloxy)phenoxy)methyl)oxirane | HCID 119882 | — |
| 反応物 | 1-(2,5-Dimethoxyphenyl)piperazine dihydrochloride | HCID 13599003 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | HCID 22625376 | HCID 22625376 | 33.9% |
反応手順
2.56 g of 1-(4-benzyloxyphenoxy)-2,3-epoxypropane was dissolved in 100 ml of dioxane, and to this were added 2.95 g of 1-(2,5-dimethoxyphenyl)piperazine dihydrochloride and 3.5 ml of triethylamine and reaction and workup were carried out as in Example 1-A. The residue obtained was purified by column chromatography (silica gel, elution with ethyl acetate:hexane=1:1) to give 1.62 g of brown oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06358515B2 |
| 出典データセット | uspto-grants-2002_03 |
| ORD ID | ord-74ab6cf6ea5342a989d4f284f57cbbbb |
| 出典メモ | uspto-grants-2002_03 |