関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Sodium Hypochlorite | HCID 23665760 | — |
| 反応物 | Ammonium 3-nitrophthalamidate | HCID 70153617 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-Amino-3-nitrobenzoic acid | HCID 219633 | — |
反応手順
22 g (105.2 mmol) of ammonium 3-nitrophthalamidate (1a) were treated with stirring with 165 ml of sodium hypochlorite solution. After 5 minutes, a solution of 8.8 g of sodium hydroxide in 22 ml of water was added and the mixture was then stirred at 70° C. for 1 h. The suspension was poured into 500 ml of water with stirring. The resulting clear solution was acidified with concentrated HCl. The precipitate was filtered off and dried in a desiccator. Yield: 9.68 g (51%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06358978B1 |
|---|
| 出典データセット | uspto-grants-2002_03 |
|---|
| ORD ID | ord-5f008454695c42c0ba33289a88e46f8d |
|---|
| 出典メモ | uspto-grants-2002_03 |
|---|
